Vol. 9, Special Issue 2 (2024)

Author(s): GM Makwana, PB Patel, AM Patel, JB Patel, MJ Desai and DK Parmar

Abstract: The present investigation was conducted on 18 bovines (14 buffalo and 4 cattle) to study comparative evaluation of 0.25% Bupivacaine HCL, 0.5% Bupivacaine HCL and 2% Lignocaine HCL for proximal paravertebral nerve block in bovines. Bupivacaine was found to haveno clinically relevant effects on heart rate, respiration rate and rectal temperature. 0.5% Bupivacaine did not show any adverse clinical effect on the haematological and physiological parameters. Non-significant decreased in serum cortisol was observed 30 minutes after administration of local anesthetics compare to before administration of local anesthetics in all groups and quantified that the local anaesthetic reduced surgical stress during surgical procedures. From the present study, it was concluded that 0.5% Bupivacaine effectively administrated in paravertebral space in physiologically impaired animals.