Vol. 9, Special Issue 2 (2024)

Author(s): Falguni D Modi, Rasesh D Varia and Jatin H Patel

Abstract: Lemongrass, or Cymbopogon flexuosus, is a perennial grass of the Poaceae family's genus Cymbopogon. The antimicrobial activity of lemon grass leaf methanol and aqueous extracts was evaluated using the Microbroth dilution technique against a variety of bacteria at varying concentrations, including Salmonella Typhimurium, Escherichia coli, Pseudomonas aeruginosa, Proteus mirabilis, Bacillus subtillis and Streptococcus pyogenes. Apart from Pseudomonas aeruginosa and Proteus mirabilis, the outcomes showed that the lemongrass methanol extract exhibited effective antibacterial activity against all test species. At a dose of 20.48 mg/ml, the plant's methanol extract had inhibitory effects on Salmonella Typhimurium, Escherichia coli, and Staphylococcus aureus organisms. For Bacillus subtillis and Streptococcus pyogenes, the lemongrass methanol extract's minimum inhibitory concentration (MIC) was 1.28 mg/ml and 0.32 mg/ml, respectively. The findings indicate that the extract from the leaves of Cymbopogon flexuosus (lemongrass) has robust antibacterial properties in opposition to each gram-effective and gram-negative bacteria. Extracts from the leaves of Cymbopogon flexuosus have the capability to assist the plant's use as a natural antibacterial agent.