Vol. 9, Special Issue 1 (2024)

Author(s): Neeti Kopal Bante, Renuka Mishra, Shraddha Sinha, SK Maiti, HK Ratre and Saleema Ahmed Quadsri

Abstract: The unplanned mating of stray dogs is one of the major reason for increasing population of pet dogs The study was carried out at the Department of Teaching Veterinary Clinical Complex, College of Veterinary Science and Animal Husbandry, Anjora, Durg, Chhattisgarh, India during June to November, 2023 in twelve female dogs to evaluate the efficacy of estradiol benzoate in mismating in dogs to prevent pregnancy. The information of mismated female dogs regarding breeding records, day of mismating, history of proestrual bleeding and mating history were collected by owners and dog breeders. Physical examination including rectal temperature, heart rate and respiration rate were recorded as early as possible after mating. Based on the starting of treatment postmating, mismated dogs were allocated into 3 groups. All the affected dogs were given three doses of estradiol benzoate (Injection PREGHEAT, Virbac, 2 ml, 1 mg/ml) intramuscularly at dose rate of 0.02 mg/kg body weight at alternate days. Group I, II and III includes affected dogs with their first dose of estradiaol in between 1-3, 4-6 and 7-12 days postmating, respectively. The comparative efficacy of estradiol benzoate administered between day 1 to day 15 post mating was evaluated in terms of conception rate between different groups. The confirmation of pregnancy was done by transabdominal ultrasonography on 30 days postmating. Group I and II shows 100% efficacy of estradiol benzoate while group III is limited to 50% efficacy of estradiol treatment for mismating. Dogs were effectively and safely treated from conceiving and getting pregnant with three dosage of 0.02 mg/kg of Estradiol benzoate within 7 days postmating in mismated dogs.