Vol. 8, Special Issue 2 (2023)

Author(s): Komal, Amandeep and Ritu

Abstract: Mastitis, being a multi-etiological disease, therefore it cannot be cured, however it can be controlled to a minor degree. Highly producing bovines suffer from mastitis widely but buffalo is comparatively less susceptible to mastitis because of its longer teats as well as thicker teat canal epithelium than cattle. This can be accomplished by breeding techniques, a decrease in pathogen exposure, and an increase in intramammary infection resistance. A generally advocated strategy, however, is marker assisted selection (MAS) using a candidate gene approach, which is focused on enhancing the host genetics. These genes are related to immune system including Toll-like receptor (TLR) genes which somehow are responsible for mastitis resistance, glycoprotein receptors, lactoferrin gene, neuropeptide receptors, etc., which are responsible for mastitis susceptibility and resistance. This review illustrates briefly a number of candidate gene identified for mastitis in bovines and also the methods to identify such candidate genes.