Canine demodicosis is a common parasitic dermatological disorder caused by excessive proliferation of Demodex canis, particularly in immunocompromised and genetically predisposed dogs. The present study reports a clinical case series of six dogs affected with demodicosis, emphasizing clinical presentation, diagnostic confirmation, therapeutic management, and treatment outcomes. Dogs of different breeds and ages presented with dermatological lesions including erythema, alopecia, papules, ulceration, and pruritus of varying severity. Diagnosis was confirmed by deep skin scraping and trichogram examination. All cases were treated using an ivermectin-based therapeutic protocol along with antibiotics, anti-inflammatory drugs, topical benzoyl peroxide shampoo, and supportive therapy. Clinical recovery was observed in all cases within 10-21 days, with generalized cases requiring longer treatment duration. The study highlights the efficacy of ivermectin-based therapy combined with supportive management in the successful resolution of canine demodicosis