Vol. 10, Issue 8, Part C (2025)

Author(s): C Balan

Abstract: Ketosis remains one of the most significant metabolic disorders affecting dairy production worldwide. This study aimed to conduct a meta-analysis to estimate the pooled prevalence of clinical (CK) and subclinical ketosis (SCK) in dairy bovines across India using published literature from various regions. The findings indicate a substantial burden of ketosis among dairy animals in India, with crossbred cows particularly susceptible, especially during the early postpartum period. A meta-analysis of 12 published research studies from 1996-2023 assessed the prevalence of ketosis in India across dairy cows and buffaloes. Data were analyzed using the ‘meta’ package in R with a generalized linear mixed model and Logit transformation. A random-effects model estimated pooled prevalence rates for clinical and subclinical ketosis. The pooled prevalence of subclinical ketosis was estimated at 13% (95% Confidence Interval [CI]: 7%-22%), with a Prediction Interval (PI) of 1%-63%, based on 4,314 dairy bovine samples. Significant heterogeneity was observed across studies (I² =95.0%, ?² =1.23, Q =301.38 (p?0.01). Similarly, the pooled prevalence of clinical ketosis was 11% (95% CI: 6%-18%), with a PI of 2%-47%, based on 7,880 samples. Heterogeneity remained high (I² =97.6%, ?² =0.74, Q =416.02, (p? 0.01).