Vol. 10, Issue 8, Part B (2025)

Author(s): Saravanan M and Vigneshwaran B

Abstract: This case report describes the clinical management of piroplasmosis in a 5-year-old crossbred Jersey cow presenting with hemoglobinuria, pyrexia, and severe anaemia. Diagnosis was confirmed through blood smear microscopy revealing 20% parasitemia with Babesia spp. The animal was treated successfully with diminazene aceturate (3 mg/kg IM), long-acting oxytetracycline (20 mg/kg IM), and supportive therapy including hematinic and fluid therapy. Despite therapeutic success in this case, babesiosis remains a significant threat to cattle health, causing substantial economic losses through mortality, reduced productivity, and treatment costs. The report highlights the importance of early diagnosis, prompt treatment, and integrated tick control measures in endemic regions. Key challenges include emerging drug resistance and the limitations of current diagnostic methods, underscoring the need for improved detection techniques and alternative therapeutics.