Investigation of the in vitro antibacterial potential of a polyherbal extract against Escherichia coli
Author(s): Devang Chaudhari, Falguni Modi, Jatin Patel, Rasesh Vari, Ankit Patel and Naitik Patel
Abstract: Antimicrobial resistance is a cosmopolitan issue for poultry industry. Avian pathogenic E. coli (APEC) is causative agent for the avian collibacillosis which is resistant to many antibiotics (exa. ?-lactams and aminoglycosides). Alternative to antimicrobial drugs such as polyherbal can act as natural antimicrobial source to lessen the antimicrobial resistant. Under this aim present study was conducted to evaluate in vitro antimicrobial activity of polyherbal extract against E. coli O78. Minimum Inhibitory Concentration (MIC) of polyherbal hydromethanolic extract (50:50) was determined with using standard protocol of micro broth dilution technique with some modification. The Polyherbal formulation included Clove (Syzygium aromaticum), Amla (Emblica officinalis), Saunf (Foeniculum vulgare), Sunth (Zingiber officinale), Ajwain (Trachyspermum ammi), Garlic (Allium sativum), Tulsi (Ocimum sanctum), Ashwagandha (Withania somnifera) and Galo (Tinospora cordifolia). The Minimum inhibitory concentration of polyherbal hydromethanolic extract (50:50) against E. coli was found at 6.25 mg/mL, which is indicative of in vitro effect of current polyherbal formulation. The presence of different phytochemicals from different plants are responsible for the antimicrobial activity of the polyherbal formulation.
How to cite this article:
Devang Chaudhari, Falguni Modi, Jatin Patel, Rasesh Vari, Ankit Patel, Naitik Patel. Investigation of the in vitro antibacterial potential of a polyherbal extract against Escherichia coli. Int J Vet Sci Anim Husbandry 2025;10(8):99-103.
