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Vol. 10, Issue 8, Part A (2025)

Ocular Mast Cell Tumour (MCT) in a mongrel dog: Cytological and immunocytochemical diagnosis

Author(s): KS Rugmini, S Subapriya, GVS Rao, H Pushkin Raj, C Niranjana and Mohamed Shafiuzama
Abstract: This report describes a case of Ocular Mast Cell Tumour (MCT) diagnosed by cytological and immunocytochemical evaluation in a ten-year-old male mongrel dog presented to the Ophthalmology unit, Surgery, of Madras Veterinary College Teaching Hospital (MVCTH) with a six-month history of a progressively enlarging, ulcerating mass of the Right Upper Eyelid (OD). Ophthalmological examination revealed prolapse of the third eyelid membrane. Fine Needle Aspiration Cytology (FNAC) of the eyelid mass demonstrated numerous discrete mast cells containing characteristic intracytoplasmic metachromatic granules. Subsequent immunocytochemical analysis of the aspirate revealed discrete mast cells with intracytoplasmic metachromatic granules.Subsequent immunocytochemical analysis of the aspirate showed strong and diffuse expression of c-Kit leading to confirmatory diagnosis of mast cell tumour.
Pages: 13-15  |  505 Views  6 Downloads


International Journal of Veterinary Sciences and Animal Husbandry
How to cite this article:
KS Rugmini, S Subapriya, GVS Rao, H Pushkin Raj, C Niranjana, Mohamed Shafiuzama. Ocular Mast Cell Tumour (MCT) in a mongrel dog: Cytological and immunocytochemical diagnosis. Int J Vet Sci Anim Husbandry 2025;10(8):13-15.
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International Journal of Veterinary Sciences and Animal Husbandry