Vol. 10, Issue 4, Part F (2025)

Author(s): Jian Ebraheem, Muhammed Mizher Radhi and Asmaa Abdulsattar Obaid

Abstract: Electrochemical sensors have gained significant importance due to their sensitivity, speed, and cost-effectiveness in detecting ions in biological fluids. Magnesium sulfate (MgSO₄), commonly used in therapeutic interventions, affects the electrolyte balance in blood. Understanding its electrochemical interactions, particularly on glassy carbon electrodes (GCEs), is crucial for developing diagnostic methodologies in animal models such as rabbits. This study investigates the electrochemical behavior of magnesium sulfate (MgSO₄) at the interfaces of glassy carbon electrodes (GCEs) within rabbit blood matrices, providing insights into the detection capabilities and performance of the electrodes. Glassy carbon electrode (GCE) was used to observed the chemical properties of magnesium sulfate solution in electrolyte of rabbit's blood medium by cyclic voltammetry. The study was aimed to find the electrochemical behavior of magnesium ions Mg(II) in the blood samples to find redox reaction. The study focused on the redox reaction of current peaks for magnesium ions in blood. The results were found one of reduction current peak appeared at -0.8 V. The research included different voltammetric study for the cathodic current peak of Mg ions, such as in different concentrations, scan rates, pH, and reliability in blood medium. A low detection limit was found of Mg(II) at 0.1-0.4 mM, with good linear of relationship of different scan rates and high sensitivity of 0.9914. Also, the cathodic current peak of Mg ions was enhanced at alkaline blood solution of pH 8-10. So, we can said that magnesium compound in blood medium act as anti-oxidative reagent, which can used as a nutritional supplements, and causes its deficiency in the human body to serious health effects.

DOI: 10.22271/veterinary.2025.v10.i4f.2226