Diagnosis of bovine tuberculosis: A review
Author(s): Akshay Garg, Poonam Shakya, RP Singh and Pradeep Kumar Singh
Abstract: Bovine Tuberculosis (bTB), caused by Mycobacterium bovis, remains a major concern in veterinary medicine due to its impact on animal health, economic stability, and public safety. Effective diagnosis is essential for disease control, with traditional methods such as the intradermal tuberculin test serving as the gold standard. However, advancements in molecular diagnostics, serological testing, and point-of-care technologies are enhancing detection accuracy and efficiency. Emerging techniques, including rapid polymerase chain reaction (RPA) and whole-genome sequencing, offer promising alternatives for improving bTB management, particularly in resource-limited settings. Despite progress, challenges such as false negatives, wildlife reservoirs, and long incubation periods for microbial cultures persist. Continued research and the integration of novel diagnostic tools with conventional methods are crucial for early detection, prevention, and eradication of bTB. This comprehensive approach will strengthen disease control strategies, safeguard public health, and support the sustainability of livestock industries worldwide.