Hypomagnesemia-induced hypocalcemia: Effects on erythrocyte membrane stability in lactating jersey and Holstein-Friesian crossbreed dairy cattle
Author(s): Rameshkumar Ganesan, Prasanth D, Vijay Kannan, Prabakar G and Sathyabama T
Abstract: This study compared blood minerals, hematological parameters, and erythrocyte fragility in Jersey Cross (JX) and Holstein-Friesian Cross (HFX) cattle breeds. Significant breed differences were observed in serum calcium levels (JX: 4.34±0.17 mg/dL vs. HFX: 6.26±0.26 mg/dL, p<0.001), serum magnesium levels (JX: 0.93±0.05 mg/dL vs. HFX: 1.60±0.05 mg/dL, p<0.001), hemoglobin levels (JX: 4.81±0.16 g/dL vs. HFX: 5.65±0.25 g/dL, p<0.001), mean corpuscular volume values (JX: 64.06±0.98 fL vs. HFX: 75.95±0.99 fL, p<0.001), and erythrocyte fragility (JX: 0.10±0.02 vs. HFX: 0.34±0.02, p<0.001). No significant differences were observed in red blood cell count, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, and packed cell volume. These findings suggest that magnesium deficiency may contribute to oxidative stress and cellular dysfunction in JX cattle, and that the erythrocyte fragility test can inform proactive strategies to counteract these effects.