Hypothyroidism in a geriatric labrador retriever: Clinical diagnosis and therapeutic management
Author(s): Surendar AP and Dharani M
Abstract: Canine hypothyroidism is a commonly reported endocrine disorder, particularly in aging, large-breed dogs, resulting from inadequate secretion of thyroid hormones and leading to metabolic, dermatological, and systemic alterations. This case report describes hypothyroidism (serum T3 level: 0.52 ng/ml) in a 10-year-old Labrador Retriever presented with lethargy, progressive weight gain, and chronic dermatological abnormalities. Diagnosis was established based on clinical signs, supportive hematobiochemical findings, and decreased serum total thyroxine concentration. The treatment protocol included oral levothyroxine at a dose of 22 µg/kg body weight, fexofenadine hydrochloride at 4 mg/kg, ketoconazole at 5 mg/kg, along with supportive therapy comprising LivFit syrup (15 ml twice daily) and GlowCoat syrup (15 ml twice daily). Topical management involved bathing with Nuforce NF Pet shampoo twice weekly for one month, followed by Keramed Vet shampoo once weekly. Therapy was continued for a total duration of six months. Marked clinical improvement was observed within three months of treatment, with significant resolution of lethargy and skin lesions. After six months of therapy, serum thyroxine levels increased to 0.79 ng/ml, following which antifungal therapy and nutritional supplements were gradually discontinued. This report highlights the importance of considering hypothyroidism as a differential diagnosis in geriatric dogs presenting with nonspecific clinical signs and chronic dermatological conditions, and emphasizes the effectiveness of appropriate hormone replacement and supportive therapy.
