Vol. 10, Issue 12, Part E (2025)

Author(s): Naveena M, Suganya G, Loganathasamy K and Balagangatharathilagar M

Abstract: The present study aimed to evaluate the hemato-biochemical alterations associated with renal dysfunction in dogs through comprehensive haemato-biochemical profile. A total of 57 dogs were divided into three groups: control (N=12), acute kidney injury (AKI) suspected (N=7), and chronic kidney disease (CKD) affected (N=38). Haematological evaluation revealed a significant (p<0.01) decrease in haemoglobin, packed cell volume, and total erythrocyte count in both AKI and CKD groups, indicating anaemia of renal origin. AKI dogs exhibited a significantly higher neutrophil percentage (p<0.05) suggestive of systemic inflammation. Biochemical analysis showed markedly elevated (p<0.01) blood urea nitrogen and serum creatinine levels in renal-compromised groups, confirming azotemia. In conclusion, renal dysfunction in dogs was characterized by anaemia and azotemia emphasizing the diagnostic importance of detailed hematobiochemical evaluation for early identification and differentiation of AKI and CKD.

DOI: 10.22271/veterinary.2025.v10.i12e.2833