A review on oxidative stress in small ruminants induced by helminthes
Author(s): Prajna Sarita Sethy and Mukta Mayee Kumbhar
Abstract: In this paper, the most recent findings about the oxidative stress that helminth parasites cause in small ruminants like sheep, goat are reviewed. As a by-product of regular cell metabolism, an imbalance between the production of oxidant and antioxidant components results in oxidative stress. Many of these molecules are essential components of numerous metabolic pathways. Numerous Reactive Oxygen Species (ROS) are produced by the body, but these are countered by an antioxidant defence mechanism that keeps the concentrations of these oxidising substances below tolerable limits. There are a few reasons why this is the case. Helminth infection is a contributing factor. The most widespread and economically significant infectious illness in the world, gastrointestinal helminth infections kill millions of animals each year, mostly cattle, sheep and goats. ROS causes lipid peroxidation, protein oxidation, gene expression alterations, redox status changes, certain diseases, and accelerated aging in small ruminants.
