Vol. 10, Issue 11, Part B (2025)

The study assessed haemato-biochemical responses during fracture healing in dogs treated with stainless-steel and titanium dynamic compression plates (DCPs). Twelve dogs with diaphyseal radius-ulna fractures were randomly divided into two groups (n = 6 each) and managed by open reduction and internal fixation using either stainless-steel or titanium DCPs. Haematological and biochemical parameters were evaluated up to 90 postoperative days. Both groups showed transient postoperative decreases in haemoglobin, packed cell volume, and total erythrocyte count, which normalized by day 7. Serum alkaline phosphatase and phosphorus increased during early osteogenesis and declined as remodelling progressed, while calcium showed a biphasic trend. Titanium implants showed earlier normalization of leukocyte count, ALP, and phosphorus levels, indicating reduced inflammation and faster metabolic recovery. Both materials were biocompatible and effective for fracture stabilization; however, titanium DCPs demonstrated superior healing dynamics and clinical outcomes, supporting their preference for canine long bone fixation.