Histoarchitecture of endocrine pancreas of dog and pig
Author(s): S Dhilleswara Rao, P Jagapathi Ramayya, M Santhi Lakshmi, RV Suresh Kumar and B Rambabu Naik
Abstract: The present study comparatively evaluated the endocrine pancreas of dogs and pigs with reference to islet of Langerhans morphology and cellular composition. In both species, the islets of Langerhans were irregularly distributed among the acini and surrounded by sinusoidal capillaries and fine reticular fibres. Dogs exhibited three types of islets i.e large sized measuring 80 to 110 ?m, medium sized 40 to 45 ?m, and small sized 20 to 25 ?m while, pigs possessed comparatively larger islets of Langerhans measuring 145 to 230 ?m, 60 to 110 ?m, and 20 to 30 ?m, respectively. The number of endocrine cells per islet of Langerhans was lower in dogs (38–50, 16–20, and 1–7) than in pigs (105–123, 25–34, and 1–15). ?-cells were predominant in both species, constituting 60.72 to 73.01% in dogs and 73.38 to 73.04% in pigs, whereas ?, ?, and PP cells were fewer. Overall, the islets were larger, denser, and more numerous in pigs, indicating higher endocrine activity compared to dogs.
