Background: Phosphorus deficiency (hypophosphatemia) is a widespread nutritional constraint for livestock in India, primarily due to low phosphorus levels in soil, plants, and fodder, compounded by the high demand of lactation in dairy animals. This essential mineral is crucial for ATP generation, bone structure, and numerous physiological processes.
Objective: This study aimed to evaluate the comparative efficacy of an Organic Phosphinate (Toldimfos sodium) versus an Inorganic Phosphate (sodium acid phosphate) in correcting hypophosphatemia in cross-bred Holstein Friesian (HF) cows.
Methods: Twenty HF cross cows in the Banaskantha district exhibiting clinical signs of chronic phosphorus deficiency (e.g., rough coat, pica/chewing of inanimate objects, reduced milk yield, reduced feed intake, and infertility) and having a serum inorganic phosphorus (Pi) level below the critical level (5.6 mg/dl) were divided into two groups (n=10 each). Group A received Sodium Acid Phosphate (Inorganic Phosphate) @ 15 ml intravenously, and Group B received Toldimfos Sodium (Organic Phosphinate) @ 15 ml intravenously. Serum Pi levels were measured before treatment (0 hour) and 24 hours post-treatment.
Results: Both treatments resulted in a significant increase (P<0.05) in serum Pi levels.
· Group A (Inorganic Phosphate): Mean serum Pi increased from 4.828±0.1925 mg/dl to 6.104±0.2927 mg/dl, representing a 26.43% increase.
· Group B (Organic Phosphinate): Mean serum Pi increased from 4.011±0.1583 mg/dl to 4.744±0.2615 mg/dl, representing an 18.27% increase.
The Inorganic Phosphate preparation (Sodium Acid Phosphate) showed a markedly higher and faster increase in serum phosphorus levels compared to the Organic Phosphinate, suggesting its rapid absorption and distribution.
Conclusion: Inorganic Phosphate preparations, specifically Sodium Acid Phosphate, are more efficacious than Organic Phosphinate (Toldimfos sodium) for the rapid correction of acute or chronic hypo-phosphatemic conditions in HF cross cows.
International Journal of Veterinary Sciences and Animal Husbandry
