Vol. 10, Issue 10, Part B (2025)

Author(s): Rejitha Joseph

Abstract: A study was conducted on twelve crossbred cattle at Thiruvambadi Grama Panchayat in Kozhikode district to evaluate the efficacy of different intrauterine antibiotic preparations in treating infertility. Six animals were treated with intrauterine cephalexin (4 g), while the remaining six received a combination of oxytetracycline (1.5 g/30 ml) and metronidazole (150 mg/30 ml). Following antibiotic therapy, one estrus cycle was discarded to allow natural uterine cleansing. Ten days after estrus, the presence of a functional corpus luteum was confirmed, after which two doses of a prostaglandin analogue were administered intramuscularly at an interval of 11 days. Artificial insemination (AI) was performed on the 3^rd and 4^th days following the final prostaglandin injection, and pregnancy was confirmed 90 days later by rectal palpation. None of the cephalexin-treated animals conceived, whereas four out of six animals treated with the oxytetracycline-metronidazole combination conceived. The findings suggest that the oxytetracycline-metronidazole combination is effective in improving conception rates in repeat-breeding cattle, whereas cephalexin was ineffective under field conditions in Thiruvambadi, Kozhikode.

DOI: 10.22271/veterinary.2025.v10.i10b.2617