Vol. 9, Special Issue 6, Part D (2024)

Author(s): VI Borekar, AP Somkuwar, AR Sawarkar, RP Limsay, SA Dubey and SA Umap

Abstract: The present research investigation was carried out to study effect of 50% ethanolic rhizome extract of Z. Officinale on serum biochemical parameters on Lead induced toxicity in broiler birds. 140 broiler chicks were divided into 7 groups each comprising of 20 birds. The toxicity was induced by administration of lead acetate @200 mg/kg feed from T₂ to T₇ and T₁ as normal control. T₃ & T₄ was given AA @200 mg/kg feed & Ext. @200 mg/kg b.w, respectively. T₅ was given AA @200 mg/kg feed & Ext. @200 mg/kg b.w. T₆ was given Ext. @300 mg/kg b.w. b.w, respectively. At the end of experiment, it was observed that, Z. officinale rhizomes extract @ 200 and 300 mg/kg bw alone and with L-ascorbic acid has effectively reduced AST, ALT & ALP level and subsequently improved the serum protein & albumin level in of broiler birds. Further, increased BUN & creatinine level due to lead toxicity were also restored. Histopathological study revealed that altered histoarchitectural changes due to lead toxicity were ameliorated with restoration of liver tissues by 50% ethanolic extract alone and with ascorbic acid (T₃, T₄, T₅, T₆ and T₇) which confirmed the protective ability of Z oficinale and L-ascorbic acid in broiler chickens.