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Vol. 9, Issue 6, Part G (2024)

A clinical study on clinical evaluation of eggshell derived nano hydroxyapatite on augmenting healing of long bone fractures in dogs

Author(s): Durgude Sudrshan Ravindra, V Devi Prasad, Ravi Kumar, Lakshmi Rani and Vivekananda Kattimani
Abstract: Among 158, 126 were long bone fractures accounting for 3.78% of total cases and 79.74% of fracture cases. The highest incidence was recorded in Mongrel dogs in the juvenile age group, male dogs, right hind limb and femur bone. The most frequent cause of fractures in the present study was automobile accidents. Out of 12 cases, fractures of radius ulna (N=6), tibio-fibula (N=5) and femur (N=1) were selected and were randomly divided in to two groups of six each. In group I, repair of fractures was done by DCP and in group II, along with bone plating, eHA was applied at the fracture site under general anaesthesia. Cranio-medial approach for the radius and ulna cranio-lateral approach for the femur and cranio-medial approach for the tibio-fibula were adopted. Lower values of ALP were recorded during the preoperative and immediate postoperative days which then increased significantly. Lower values of serum calcium and phosphorus were recorded initially in group I and higher values observed in group II. Lower values of serum vitamin D were recorded that increased significantly (p<0.05) from 7th to 60th postoperative day bone remodeling with corticomedullary continuity was recorded in majority of group II dogs when compared to those of group I by the end of 90th postoperative day. At various periodic intervals of the present study, group II had better mean fracture healing scores than group I, suggesting the impact of eggshell derived nano hydroxyapatite on augmenting healing of long bone fractures in dogs. Pedal edema observed in case 5 of group I in the immediate postoperative period was attributed to application of tight bandage. Group-II dogs showed better outcome than those of group-I which could be attributed to the application of eggshell derived nano hydroxyapatite at the fracture gap after fracture fixation with DCP. It can be concluded that DCP is a versatile and stable repair procedure that enabled rapid weight bearing for transverse fractures of the long bones. The eHA is an affective biomaterial which can induce the osteoblastic activity and Vitamin D supplementation following repair of long bone fractures can have a bearing on the restoration of ambulation following bone plating.
Pages: 446-455  |  102 Views  5 Downloads


International Journal of Veterinary Sciences and Animal Husbandry
How to cite this article:
Durgude Sudrshan Ravindra, V Devi Prasad, Ravi Kumar, Lakshmi Rani, Vivekananda Kattimani. A clinical study on clinical evaluation of eggshell derived nano hydroxyapatite on augmenting healing of long bone fractures in dogs. Int J Vet Sci Anim Husbandry 2024;9(6):446-455. DOI: https://doi.org/10.22271/veterinary.2024.v9.i6g.1913
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International Journal of Veterinary Sciences and Animal Husbandry