Abstract: Bovine mastitis is a prevalent disease in India's dairy cattle, significantly impacting animal health, milk quality, and production, leading to estimated economic losses of approximately Rs 70 billion annually. The indiscriminate use of antibiotics for treatment not only escalates costs but also contributes to antimicrobial resistance (AMR). This study explores the efficacy of ethno-veterinary herbal formulations as a cost-effective alternative to conventional treatments. Conducted across Guntur, Karimnagar, and Mysuru, 279 cases were treated with herbal mixtures containing Aloe Vera, turmeric, and calcium hydroxide. Results indicated an 89% recovery rate, highlighting the potential of ethno-veterinary practices in managing mastitis while reducing antibiotic use. Further research is recommended to enhance adoption and assess effectiveness in diverse settings..