Vol. 9, Issue 4, Part J (2024)

Author(s): Jay K Desai, Bhavesh J Trangadia, Urvesh D Patel, Amit R Bhadaniya, Bhavesh B Javia and Mayank H Kariya

Abstract: The phenolic endocrine disruptor compound 4-nonylphenol (4-NP) is present in many industrial product and also present in the environment which is responsible for having impact of health of humans and animals including aquatic species. There is need to evaluate the toxic effect of this pollutant on the eye of aquatic species. With this aim, the study was conducted on adult male zebrafish which were exposed to 100 and 200 μg 4-NP /L of water for 21 days. At the end of the study, evaluated histological alterations in the retina of zebrafish eye. A total of 24 adult zebrafish were divided into 4 groups. Zebrafish of first group was kept unexposed (normal control) while second group was exposed to ethanol at 10 μl/L of water and considered as vehicle group. Fish of two toxicity groups were exposed to 4-NP (100 and 200 μg 4-NP /L of water). However, remarkable microscopic lesions in the retina was found only in the higher toxicity group.