Treatment of meloxicam induced acute kidney injury by intermittent hemodialysis
Author(s): Randhir Singh, Sachin and Rajsukhbir Singh
Abstract:
A case of 1.2 years old Golden retriever breed dog with history of shivering, dullness, anorexia and 3-4 episodes of vomiting since past 15 days was presented in dialysis unit, multispecialty veterinary hospital, Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana, Punjab. Dog was administered a single dose of parenteral oxytetracycline @ 3.5 ml IV and dexamethasone 1ml IV followed by injection Melonex Plus 2.5 ml IM for 15 days. On presentation, the dog was dull and laboratory findings revealed BUN- 101mg/dL, Creatinine- 11.7mg/dL, Na- 139mEq/L, K- 6.1mEq/L, Cl- 106mEq/L, P- 10.5mg/dL and Ca- 10.8 mg/dL. Serum total protein and albumin were 6.9g/dL and 3.3g/dL, respectively. Abdominal ultrasound revealed both kidneys hyperechoic with mild to moderate loss of cortico-medullary differentiation. As the dog was already on fluids and diuretics from past 4 days without any promising results, intermittent hemodialysis (IHD) was preferred as a treatment modality of choice to save dog’s life. The dog was put on IHD and after dialysis the dog showed good recovery without any further signs of renal injury even after six months of dialysis.