Vol. 9, Issue 2, Part E (2024)

Author(s): Sachin Kalaswa, Ravindra Jadav and HC Nakhashi

Abstract: Clinical indicators of pseudopregnancy include weight gain, lactation, growth of the mammary glands and nesting behaviour in non-pregnant Bitches (dogs). It usually happens six to twelve weeks after estrus in non-pregnant bitches. Based on the owner's history, clinical symptoms, hematology, vaginal cytology, hormonal changes and a thorough radiographic and ultrasonographic examination, an early and highly advanced diagnosis is made. The exact cause of clinical pseudopregnancy remains unclear, despite prolactin's pivotal involvement in its symptomology. According to some research, bitches that are openly pseudopregnant see an increase in circulating prolactin concentrations during diestrus, relative to bitches that are not affected. The variance in the prevalence and severity of pseudopregnancy within and across breeds may possibly be due to individual variability in peripheral sensitivity to prolactin, or even the existence of molecular variants of canine prolactin with varying bioactivities. Based on the effects of exogenous progesterone and the frequent induction of pseudopregnancy by spaying during the luteal phase in the metestrus stage of the cycle, exposure to progesterone and subsequent removal of progesterone appear to be involved. Since overt pseudopregnancy is typically a self-limiting and perhaps quasi-physiological state, modest cases are typically either deemed not requiring treatment or are not brought forward for therapy. both with non-surgical or surgical management and homoeopathic treatment. The side effects of sex steroids, especially oestrogens, androgens and progestins, which are typically used to treat pseudopregnancy, outweigh any benefits. However, when available, oestrogens like diethylstilbestrol, oestradiol benzoate and oetsradiolcypionate, androgens like mibolerone and progestins like megestrol acetate and medroxyprogesterone may be helpful. It has been demonstrated that the injection of an ergot derivative, such as bromocriptine, cabergoline or metergoline, effectively inhibits the release of prolactin and is a more suitable treatment for canine pseudopregnancy than the use of steroids. Although many ergot derivatives may have undesirable side effects, these are usually mild and easily tolerated or controlled. Very good, side-effect-free homoeopathic therapies for pseudopregnant bitches with Thuja occidentalis and Urtica urens. Because ovariectomy is the sole long-term preventative strategy, predisposed bitches who are not meant for breeding should be spayed. The aim of this study is to promote awareness on the benefits of early diagnosis and excellent medical, homoeopathic, and surgical/non-surgical care for pseudo-pregnant patients without complications.