Vol. 9, Issue 2, Part A (2024)

Author(s): N Yadav, S Nath, G Das, S Kumar, R Verma, V Punia, D Kumawat, N Reddy and S Mandal

Abstract: The present study was carried out to assess the In vitro anthelmintic activity of Curcuma Longa (turmeric) gastrointestinal strongyles infecting goats. Aqueous, methanolic and hydroethanolic extracts of both the plants were prepared following standard protocol. In vitro efficacies of the different extracts were investigated by egg hatch assay (EHA), larval paralysis test (LPT) and adult mortality test (AMT). In egg hatch assay, the aqueous, methanolic and hydroethanolic extracts of C. longa at 100 mg/ml exhibited 98.02%, 97.48% and 98.04% efficacy, respectively, The ED₅₀ values obtained for aqueous, methanolic and hydroethanolic extracts of C. longa were 1.262 mg/ml, 2.226 mg/ml and 1.535 mg/ml, respectively. In larval paralysis test, the aqueous, methanolic and hydroethanolic extracts of C. longa at 100 mg/ml concentration recorded an efficacy of 99.09%, 98.28% and 95.89%. The ED₅₀ values derived for aqueous, methanolic and hydroethanolic extracts of C. longa were 1.297 mg/ml, 2.077 mg/ml and 5.391 mg/ml, respectively. In adult mortality test, for methanolic extract of C. longa, highest corrected average adult mortality %, 81.91 was observed, followed by 60.48% for aqueous extract of C. longa and 50.48% for hydroethanolic extract of C. longa. The differences among the various extracts of C. longa for corrected average adult mortality % were found to be significant (p<0.05).