Vol. 9, Issue 1, Part R (2024)

Author(s): Avantika Srivastav, Ankit Jaiswal, Shyama N Prabhu, Kavisha Gangwar, Renu Singh and Neeraj Kumar Gangwar

Abstract: A postmortem examination was conducted on an 11-year-old female Labrador dog at the Department of Pathology, CoVSc & AH, DUVASU, Mathura. The dog had a history of weakness and labored breathing. During necropsy, the carcass appeared pale and anemic, with congested visceral organs including the liver, spleen, lungs and kidneys. The heart exhibited multiple raised firm nodules in both auricles. Histopathological analysis of heart samples revealed sheets of mononuclear cells with eccentric nuclei showing a distinct cartwheel or clock-faced chromatin pattern, along with anisocytosis, pleomorphism, and karyomegaly. Mitotic figures and binucleated cells were also present. Other organs showed signs of congestion upon examination. Immunohistochemistry revealed the positive immunostaining with the MUM1. Based on these findings, the diagnosis of extramedullary plasmacytoma was established highlighting its rare occurrence in canine pathology.