Vol. 9, Issue 1, Part H (2024)

Author(s): T Maharishi, Pankaj Mangal, Munesh Kumar Pushp, JP Kachhawa, Sita Ram Gupta and Rajender Yadav

Abstract: Diarrhoea is an important disease of economic importance because of high morbidity and mortality and major cause of deaths from infectious diseases in cattle calves. Due to its adverse effects on the herd's longevity, production, and immediate health, it has an adverse economic impact on livestock farmers. The present study was conducted to access the alterations of clinico-haemato-biochemical parameters in diarrhoea affected cattle calves attributed to E. coli and Salmonella spp. infection. Forty cattle calves below 3 months of age irrespective of sex and breed were selected, 10 animals apparently healthy as control group, the affected 30 animals with apparent clinical signs of diarrhoea were considered as infected group. Clinical parameters were recorded and blood as well as sera samples were collected from both groups. Clinical scores (0-3 basis) revealed healthy calves were scored as 0, whereas among diarrhoeic calves, 8 (26.67%) were with clinical score of 1, 17 (56.67%) were with clinical score of 2 and 5 (16.66%) were with clinical score of 3 and not significantly different heart rate, respiration rate, or rectal temperature. Hematology revealed significant higher values Hb, PCV, TLC, TEC and neutrophil (%), while significant lower value of Lymphocyte (%) in diarrheic calves. Serum biochemical analysis revealed significant higher values of total protein, albumin, globulin, A:G ratio and potassium while significant lower values of sodium, chloride, bicarbonate and glucose in diarrheic calves. The results of this study indicated that E. coli and Salmonella spp. causes diarrhea in cattle calves which in turns alters the clinical, hematological and biochemical profile. This study helps to understand the Pathophysiology of diarrhoea due to E. coli and Salmonella spp. and helps in adopting a good management and treatment strategy in diarrhoeic cattle calves.