Vol. 9, Issue 1, Part F (2024)

Author(s): Sunil Kumar Jangid, Ashok Prajapat, Sarjna Meena, Manish Agrawal, Naveen Kumar, Ram Kumar Gahlot, Neelam Kumari Faran and Vijay Kumar Yogi

Abstract: Canine transmissible venereal tumour (CTVT) is a unique, contagious neoplasm affecting the genital organs of dogs. In this study, the identification of tumours was accomplished utilizing both cytological and histopathological methodologies. Fine Needle Aspiration Cytology (FNAC) and impression smears were deployed for the cytological evaluations of both palpable and non-palpable neoplastic masses. A comprehensive collection of 58 samples was procured from diverse canine breeds. Within this cohort, round cell tumours were identified, constituting 13.79% of the cases. Specifically, among these round cell tumours, canine transmissible venereal tumour manifested with an incidence rate of 50%. Cytological analysis revealed sheet-like patterns, cytoplasmic vacuoles, and variations in nuclear and cellular size. Histopathology demonstrated neoplastic structures with rounded or polyhedral morphology, accompanied by anisokaryosis and anisocytosis, and noticeable mitotic figures. Neoplastic cells appeared mainly round, oval, or polyhedral in outline (Fig. 77), featuring large, round, hyperchromatic nuclei with distinctly marginal chromatin and prominent central nucleoli. Numerous mitotic figures were observed, and an increased nuclear-cytoplasmic ratio, anisocytosis, and anisokaryosis were evident cytopathological examination plays a crucial role in the initial diagnosis of CTVT, offering a non-invasive and cost-effective method to evaluate cellular characteristics.