Vol. 8, Issue 5, Part G (2023)

Author(s): Gouru Raju, Dr. K Ramchandra Reddy, Dr. K Chandrashekar Reddy and Dr. KBP Raghavender

Abstract: Pyometra is a potentially life threatening condition which requires an early diagnosis to conserve the life of the animal. The analysis of various parameters helps in the assessment of the clinical status of the bitches. This study was undertaken on canine pyometra and consisted of 12 bitches of different breeds with known breeding history and open type of pyometra. The haematological and biochemical parameters were evaluated before and at the end of treatment. The clinical cases were divided randomly into two different groups with each group consisting of six bitches. The bitches in the two groups were treated using synthetic PGF2α along with antibiotics and second group was treated with dopamine agonist prolactin inhibiting drug, i.e., (Cabergoline) along with combination of a synthetic PGF2α (Cloprostenol).Treatment of canine pyometra by the use of different drugs was found to be successful. Treatment of canine pyometra using a combination of a dopamine agonist prolactin inhibiting drug (Cabergoline) and a lower dose of synthetic PGF2α (Cloprostenol) was found to be the most effective method among the two therapeutic protocols used in the present study.