A Nine-month-old male Labrador retriever dog weighing about thirty-one kilograms was presented at the Veterinary Dispensary, Palloor, Mahe with a history of dullness, lethargy, inappetence, vomiting, and moderate tick infestation. On clinical examination, body temperature was found to be 105.5F, the oral mucous membrane was icteric, pale mucous membrane and swollen popliteal lymph node. Hematology revealed a hemoglobin level of 5.3%, a TLC of 25300 cells per µl and pleomorphic small intra-erythrocytic piroplasms of Babesia gibsoni in blood smear. Triple therapy was initiated with Oxytetracycline @ 10mg/kg body weight intravenously along with Inj. Dextrose normal saline @ 10ml/kg for three days followed by a single dose of Diminazine aceturate @ 5 mg/kg body weight and a Single shot of Inj. Imidocarb dipropionate @ 6.6mg/kg subcutaneously and 14 days apart second dose was given. Upon follow-up, the animal exhibited an uneventful recovery from the triple therapy.