Vol. 8, Issue 5, Part B (2023)

Pasteurella multocida causing pneumonic pasteurellosis is one of the most economically important infectious diseases of small ruminants having a high prevalence rate and worldwide in distribution. A total of 16 isolates were obtained from the 191 pneumonic sheep and goat. Antibiotic susceptibility testing was performed using 12 antibiotics by the disc diffusion method. In this study, we found that the P. multocida isolates were found 100% sensitive to ceftriaxone, 93.75% for cotrimoxazole and enrofloxicin, 87.5% for amoxicillin-clavulanic acid, cefotaxime and tetracycline, 81.25% for amoxicillin/sulbactum, 75% for chloramphenicol and oxacillin, 68% for gentamicin and Co-trimaxazole, 62.5% for erythromycin and 60% for Sulphadiazine. Emergence of drug resistance in the isolates warrants the judicious use of antibiotics after performing antimicrobial susceptibility testing, wherever possible.