Abstract: Pneumonia refers to inflammation of the pulmonary parenchyma which is characterized by clinical signs like depression, fever, serous to mucopurulent nasal discharge, moist coughing, increase in the respiratory rate, changes in the depth and character of respirations, coughing, abnormal breath sounds on auscultation. The present study was undertaken to analyse haematological changes, radiographic findings and therapeutic management of pneumonic buffaloes presented to TVCC, LUVAS, Hisar during April to July, 2022. Pneumonia in these animals was confirmed by the radiographic examination. A total of 2ml of blood was collected from a total of 30 buffaloes with pneumonia of varying severity. Statistical analysis of blood samples showed that there was significant association between age of pneumonia affected animals and monocytes (p=0.004). 33.33% (n=10/30) of the animals affected with severe pneumonia were of 3-6 years of age. 76.67% (n=23/30) of pneumonia affected animals have increased neutrophil count and highest number of these cases were recorded in animals of greater than 6 years of age. Animals were treated with non-steroidal anti-inflammatory drugs, bronchodilator drugs, supportive therapy with anti-oxidants etc., and antimicrobial drugs to treat bacterial infections.