Vol. 8, Issue 4, Part F (2023)

Author(s): Dr. Veldi Pavani, Dr. M Lakshman, Dr. D Madhuri and Dr. A Gopala Reddy

Abstract: A study was conducted to examination of histopathological changes in the heart of lead acetate, tetramethylthiuram disulfide and its combination induced toxic effects in broilers. Hundred day old broiler chicks divided into four groups, in each group has 25chicks. The control group fed with normal diet, lead acetate @300 ppm per day, tetramethylthiuram disulfide @60 ppm per day and its combination of lead acetate and tetramethylthiuram disulfide with same dose. Histopathologically, heart showed severe dilatation and degeneration of cardiac muscles with infiltration of inflammatory cells. Thickened wall of capillaries with congestion, haemorrhages, fibrous tissue proliferation and pyknotic nuclei of cardiac muscle were also observed.