Aim: The aim of this study is to evaluate haematological parameters in uterine-infected cows treated with Moxifloxacin.
Material and Methods: The study was conducted with 6 cows (24-36 months of age, weighing 250 – 300 Kg) on were selected for the study on the basis of white flakes or cloudy discharge from vagina on the day of estrus considered as uterine infection. Prior to the commencement of experiment, the animals will be ensured that they had no history of antibacterial and/or NSAID treatment. Moxifloxacin (Moxiwell® equivalent to 100 mg/ml Moxifloxacin, Welcome., India) was administered separately in each of six uterine-infected cows by intra-uterine (IU) route daily for next five days Blood samples and smears were collected and prepared on daily basis for five days during the treatment days was used to evaluate haematology parameters like Hb (g/dl), PCV (%), TLC (103/μl), Differential leukocyte count (%) and PMN cells were analyzed. All the data were statistically analyzed using SPSS 21.0 (SPSS Inc., Chicago) using one-way.
Results: The increase trend in Haemoglobin from Day 1 to Day 5 might showing the reduction in infection. PCV values in the present study start to rise with the treatment might be indicative of a reduction in the degree of infection and thus increasing values. TLC values after treatment of sub-clinical endometritis significantly decline. The mean PMNs on the 1st day of treatment there was a significant (p<0.05) decline in PMNs (%) subsequent post-treatment on next four days which is indicative of recovery from uterine infection by the use of moxifloxacin through the intra uterine route.
Conclusion: It was concluded that the level of Hb (g/dl), PCV (%), TLC (103/μl), Differential leukocyte count (%), and PMN (%) shows a positive effect of moxifloxacin through intrauterine route on the uterine infection.