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International Journal of Veterinary Sciences and Animal Husbandry
Vol. 7, Issue 2, Part A (2022)

Therapeutic effect of methanolic leaves extract of Solanum incanum in copper induced cardio-toxicity in Wistar rats

Author(s): IM Hassan, B Sa’idu, A Dahiru, S Sulaiman and M Adamu
Abstract: The aim of this investigation was to study the effect of garden eggs on the heart and hematological parameters of Wistar rats induced with copper toxicity. Twenty (20) rats were randomly divided into four groups of five rats each. Group A (negative control) received water only for 15 days, Group B received copper at 200 mg/kg for five days, Group C received copper at 200 mg/kg for five days then treated with garden egg at 250 mg/kg for ten days and Group D received garden egg at 250 mg/kg only for ten days. All the rats were sacrificed on day sixteen and blood was collected through cardiac puncture and analyzed. In a group induced with copper, we observed a decrease in MCV and MCH. However, the result of this study shows that copper caused changes in hematological parameters that lead to anemia, also treatment with garden egg caused a relative increase in hematological parameters which was not significant enough to protect the effect. However, the garden eggs only were able to cause polycythemia.
Pages: 31-34  |  98 Views  3 Downloads
How to cite this article:
IM Hassan, B Sa’idu, A Dahiru, S Sulaiman, M Adamu. Therapeutic effect of methanolic leaves extract of Solanum incanum in copper induced cardio-toxicity in Wistar rats. Int J Vet Sci Anim Husbandry 2022;7(2):31-34. DOI: https://doi.org/10.22271/veterinary.2022.v7.i2a.412
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International Journal of Veterinary Sciences and Animal Husbandry