Abstract: Ghrelin is a 28-amino acid peptide hormone secreated mainly from stomach in animals. Ghrelin stimulate release of growth hormone. Ghrelin works with the help of ghrelin receptors. Ghrelins main function is to increase hunger and regulate feed intake. Ghrelin performs other functions like stimulation of gastric acid secreation, helps in the regulation of carbohydrate metabolism, increase body fat content, corticosteroid release, reproductive functions and metabolic adaptation of lactation also. All these functions of ghrelin are discussed in detail in this article.