Vol. 2, Issue 4, Part A (2017)

Author(s): Hnin Wai Phyu, Saw Po Po, Si Thu Hein, Khin Thida Khaing, Mar Mar Win and Hnin Yi Soe

Abstract: Histopathological changes in liver of six male sheep were studied by feeding different levels (40%, 25% and 0%) of cottonseed cake in the total diets for two months. Liver of sheep from groups A and B revealed degeneration and necrosis of hepatocytes, degeneration of central vein and wider sinusoidal spaces. In the portal area, degeneration of branch of portal vein, hepatic arteriole and branch of bile duct, connective tissue infiltration and oedematous fluid in portal area were found. Congestion in the branch of portal vein and central vein was observed. Histopathological changes in liver of group A were more severe than that of group B. Feeding of 40% cottonseed cake in the diet caused more toxic effects to sheep than that of 25% cottonseed cake in the diet.